KOSIN UNIVERSITY COLLEGE OF MEDICINE
Search
- Page Path
- HOME > Search
- Intracranial aneurysms in autosomal dominant polycystic kidney disease
- Jung Hyun Park
- Kosin Med J. 2024;39(4):281-289. Published online December 6, 2024
- DOI: https://doi.org/10.7180/kmj.24.138
- 1,223 View
- 17 Download
-
Abstract
PDF
PubReader 
ePub
- Background
The incidence of intracranial aneurysms (ICA) is high in patients with autosomal dominant polycystic kidney disease (ADPKD). However, little is known regarding the optimal screening and treatment methods for ICA.
Methods
This study investigated the characteristics of ADPKD patients with ICA, analyzing each variable according to whether the ICA ruptured, and examined the outcomes according to the treatment method. Specifically, a retrospective study was conducted on the treatment of ICA patients with ADPKD at a single institution for 10 years, from 2013 to 2022.
Results
The mean age of the 17 enrolled ADPKD patients with ICA was 57.4 years. Surgical and endovascular treatment methods were used in four and 13 patients. Eleven patients had unruptured ICAs, and the remaining six patients had suffered subarachnoid hemorrhage (SAH). Two patients experienced neurological deficits after discharge. All patients with unruptured ICAs were discharged without any complications, although one of them underwent additional treatment 5 years later. Four patients with SAH had known ADPKD at the time of diagnosis (67%). As for the treatment method, 13 patients were treated with coiling. In a comparison of variables between unruptured ICA and SAH patients, the location of the ICA showed a statistically significant difference (p<0.05).
Conclusions
In ADPKD patients, diagnostic screening for the detection of ICA is essential, and with appropriate management, interventional endovascular treatment may be a good treatment option.
- Spontaneous Disappearance of Unruptured Intracranial Aneurysm: A Case Report
- Sang Hoon Jeong, Jung Hwan Lee, Tae Hong Lee, Chang Hwa Choi
- Kosin Med J. 2021;36(2):148-152. Published online December 31, 2021
- DOI: https://doi.org/10.7180/kmj.2021.36.2.148
- 3,179 View
- 34 Download
- 1 Citations
-
Abstract
PDFPubReader ePub
Spontaneous resolution or thrombosis of giant or ruptured intracranial aneurysms is occasionally reported. However, spontaneous resolution of unruptured aneurysms without any intervention is extremely rare. Recently, we encountered a case of spontaneous resolution of a small unruptured aneurysm of the anterior communicating artery. We describe this rare case and discuss the mechanism of resolution with a review of the related literature.
-
Citations
Citations to this article as recorded by
- A rare case report of spontaneous thrombosis in unruptured giant intracranial aneurysm
Argirina Ghassani, Achmad Firdaus Sani, Dedy Kurniawan
Radiology Case Reports.2023; 18(8): 2649. CrossRef
- A rare case report of spontaneous thrombosis in unruptured giant intracranial aneurysm
- Endovascular or Microsurgical Treatment of Intracranial Aneurysms: Single Center Analysis
- Jin Wook Kim, Won-Bae Seung, Yong Seok Park
- Kosin Med J. 2013;28(1):19-26. Published online January 19, 2013
- DOI: https://doi.org/10.7180/kmj.2013.28.1.19
- 1,768 View
- 3 Download
-
Abstract
PDFPubReader ePub
Objectives The objective of this study was to assess effectiveness and outcomes of endovascular versus microsurgical treatment for intracranial aneurysms in single hospital.
Methods This was a retrospective study, using data collected during 4 year (between 2008 and 2011) from single hospital(Kosin University Gospel Hospital). A total of 274 treated, intracranial aneurysm cases were evaluated. The measurements used were effectiveness as measured by hospital discharge outcomes: 1) mortality (in-hospital death), 2) clinical outcomes(modified Ranking Scale: mRS).
Results Among total of 274 cases, unruptured intracranial aneurysm cases were 132 cases and ruptured cases were 142 cases. Among unruptured 132 cases, 65 cases were treated by microsurgical treatment and 67 cases were treated by endovascular treatment. Among ruptured 142 cases, 61 cases were treated by microsurgical treatment and 81 cases were treated by endovascular treatment. In unruptured cases, there was not any fatal complication and same adverse outcomes (3% versus 3%). In ruptured case, in regards of treatment modality (i.e., endovascular versus microsurgical treatment), each clinical outcomes were as followings; good clinical outcome was 53.1% (43/81) versus 41.0% (25/61), moderate clinical outcome was 13.6% (1/81) versus 9.8% (6/61), severe clinical outcome was 18.5% (15/81) versus 22.9% (29/142) and fatal outcome was 14.8 (12/81) versus 26.2% (16/61).
Conclusions This analysis of single hospital data indicates that endovascular therapy is associated with significantly less morbidity, less mortality, compared with conventional microsurgical treatment for all intracranial aneurysms. Endovascular therapy, as a treatment alternative to microsurgical clipping, should be offered as a viable therapeutic option for all patients considering treatment of an intracranial aneurysm.
First
Prev
