A Case of Type III Autoimmune Polyglandular Syndrome

Article information

Kosin Med J. 2013;28(2):167-170
Publication date (electronic) : 2013 January 19
doi : https://doi.org/10.7180/kmj.2013.28.2.167
Department of Internal Medicine, College of Medicine, Kosin University, Busan, Korea
Corresponding author: Young Sik Choi, Department of Internal medicine, College of Medicine, Kosin University, 34 Amnamdong, Seo-gu, Busan, 602-702, Korea TEL: +82-51-990-6102 FAX: +82-51-990-3005 E-mail: yschoi@kosinmed.or.kr
Received 2012 February 23; 2012 March 26; Accepted 2012 April 20.

Abstract

The autoimmune polyglandular syndromes (APS) are groups of syndromes comprising a combination of endocrine and nonendocrine autoimmune diseases. Among of those four types of APS, the main characteristics of the 3 APS are autoimmune thyroid diseases associated to other autoimmune diseases, excluding Addison’s disease. Type 3 APS are also subdivided into 3A, 3B, 3C, and 3D. Recently, we experience a case of APS manifesting 3A, 3C, and 3D subtype. A 28-year-old woman developed type I diabetes. According to her medical history, she had Graves’ disease, vitiligo, auimmune hemolytic anemia and systemic lupus erythematosus (SLE). The antoantibodies associated with Graves’ disease, SLE, and type I diabetes showed positive findings. We report this case with literatures review.

Fig. 1.

Thyroid scan showed diffuse uptake of radio iodine.

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Article information Continued

Fig. 1.

Thyroid scan showed diffuse uptake of radio iodine.