Nutritional Treatment: New Strategy for Management of Chronic Pelvic Pain

Article information

Kosin Med J. 2013;28(1):7-12
Publication date (electronic) : 2013 January 19
doi : https://doi.org/10.7180/kmj.2013.28.1.7
1Department of Family Medicine, College of Medicine, Kosin University, Busan, Korea
2Department of Obstetrics and Gynecology, College of Medicine, Kosin University, Busan, Korea
Corresponding author: Heung Yeol Kim, Department of Obstetrics and Gynecology, College of Medicine, Kosin University, 34 Amnamdong, Seo-gu, Busan, 602-702, Korea TEL: +82-51-990-6226 FAX: +82-51-990-3300 E-mail: hykyale@yahoo.com
Received 2012 July 18; 2012 July 22; Accepted 2012 August 17.

Abstract

Chronic pelvic pain is a common condition in women of reproductive age and can be described as chronic nociceptive, inflammatory and neuropathic pain characterized by spontaneous pain or a response to various stimuli. Oxidative stress is a component of the inflammatory reaction associated with pain processes. Iron and NF-κ B are well-known inducers of oxidative stress, and reactive oxygen species (ROS) are associated with chronic pelvic pain and play an important role in the regulation of genes expressing immunoregulators, cytokines, and other molecules. Chronic pelvic pain treatment is often unsatisfactory and limited to symptom control. However, dietary treatment with antioxidants can improve the function of the immune system and overcome free radical damage. Therefore, dietary supplementation is suggested as a means to treat some chronic medical conditions that respond poorly to medication. In summary, dietary treatment with antioxidants could be considered for new strategy for treatment of chronic pelvic pain and may be better tolerated by patients than current treatments.

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