1Department of Surgery, Kosin University College of Medicine, Busan, Korea
2Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
Copyright © 2022 Kosin University College of Medicine.
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Conflicts of interest
No potential conflict of interest relevant to this article was reported.
Funding
None.
Author contributions
Conceptualization: BKK. Data curation: DL, JHJ. Formal analysis: DL, JHJ. Methodology: DL. Project administration: SK, YSC. Visualization: SO, BKK. Writing - original draft: SO, BKK. Writing - review & editing: KHK, YK, KWS, KY. Approval of final manuscript: all authors.
Values are presented as number (%) or mean±standard deviation..
BMI, body mass index; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; GOT, glutamic oxaloacetic transaminase; GPT, glutamic pyruvic transaminase; ALP, alkaline phosphatase; γ-GTP, gamma glutamyl transpeptidase; HUs, Hounsfield units.
Characteristics | Billroth I | Billroth II | Total gastrectomy with Roux-en-Y | p-value |
---|---|---|---|---|
No. of participants | 132 (62.3) | 47 (22.2) | 33 (15.5) | |
Sex, male/female | 79/53 | 34/12 | 27/7 | |
Age (yr) | 58.28±10.09 | 57.83±10.79 | 60.15±12.09 | 0.051 |
Weight (kg) | 62.46±10.05 | 69.16±9.08 | 65.17±11.75 | 0.002 |
Height (cm) | 163.90±8.67 | 167.35±8.45 | 165.31±6.98 | 0.037 |
BMI (kg/m2) | 23.21±2.98 | 24.74±3.35 | 23.83±3.88 | 0.046 |
Fasting glucose (mg/dL) | 101.52±26.72 | 104.13±23.20 | 94.32±10.60 | 0.744 |
HbA1c (%) | 7.33±1.82 | 7.05±1.11 | 6.18±0.64 | 0.378 |
Total cholesterol (mg/dL) | 176.12±28.92 | 179.06±36.09 | 176.97±26.62 | 0.886 |
HDL (mg/dL) | 47.86±10.30 | 46.93±14.25 | 44.76±10.91 | 0.507 |
LDL (mg/dL) | 104.08±30.28 | 97.53±38.03 | 108.29±29.29 | 0.180 |
Triglycerides (mg/dL) | 119.64±28.55 | 129.19±67.75 | 129.56±59.44 | 0.498 |
GOT (IU/L) | 24.36±8.55 | 22.98±8.31 | 25.50±9.33 | 0.598 |
GPT (IU/L) | 23.22±9.90 | 27.09±15.61 | 24.09±10.15 | 0.082 |
ALP (IU/L) | 71.99±19.41 | 66.00±19.95 | 69.74±23.43 | 0.167 |
γ-GTP (U/L) | 36.17±43.70 | 32.05±30.15 | 40.50±42.22 | 0.770 |
Liver HUs | 53.53±6.38 | 51.44±6.81 | 50.95±9.35 | 0.074 |
Spleen HUs | 45.50±3.20 | 45.32±3.67 | 44.83±3.51 | 0.568 |
Liver-to-spleen ratio | 1.180±0.144 | 1.140±0.178 | 1.140±0.165 | 0.257 |
Characteristics | Billroth I |
Billroth II |
Total gastrectomy with Roux-en-Y |
||||||
---|---|---|---|---|---|---|---|---|---|
Preoperative | 6 Months | p-value | Preoperative | 6 Months | p-value | Preoperative | 6 Months | p-value | |
Weight (kg) | 62.46±10.05 | 57.34±9.05 | 0.017 | 69.16±9.08 | 56.00±1.41 | 0.144 | 65.17±11.75 | 60.08±11.62 | 0.033 |
BMI (kg/m2) | 23.21±2.98 | 21.56±2.67 | 0.022 | 24.74±3.35 | 21.88±3.76 | 0.106 | 23.83±3.88 | 20.19±2.89 | 0.036 |
Total cholesterol (mg/dL) | 176.12±28.92 | 168.94±30.99 | 0.001 | 179.06±36.09 | 159.04±22.48 | 0.020 | 176.97±26.62 | 157.51±29.24 | <0.001 |
HDL (mg/dL) | 47.86±10.30 | 53.85±1.15 | 0.203 | 46.93±14.25 | 46.54±13.46 | 0.634 | 44.76±10.91 | 49.77±12.61 | 0.258 |
LDL (mg/dL) | 104.08±30.28 | 96.39±32.13 | 0.005 | 97.53±38.03 | 84.96±26.48 | 0.065 | 108.29±29.29 | 91.39±21.55 | 0.030 |
Triglycerides (mg/dL) | 119.64±28.55 | 116.37±57.64 | 0.708 | 129.19±67.75 | 117.92±58.41 | 0.137 | 129.56±59.44 | 108.04±39.74 | 0.048 |
GOT (IU/L) | 24.36±8.55 | 26.43±10.11 | 0.046 | 22.98±8.31 | 27.21±11.81 | 0.078 | 25.50±9.33 | 27.42±7.44 | 0.249 |
GPT (IU/L) | 23.22±9.90 | 22.46±11.54 | 0.539 | 27.09±15.61 | 28.65±21.42 | 0.922 | 24.09±10.15 | 25.00±9.90 | 0.502 |
ALP (IU/L) | 71.99±19.41 | 79.01±18.92 | <0.001 | 66.00±19.95 | 87.54±66.76 | <0.001 | 69.74±23.43 | 77.22±18.22 | 0.125 |
r-GTP (U/L) | 36.17±43.70 | 19.4±14.95 | <0.001 | 32.05±30.15 | 69.73±257.53 | 0.225 | 40.50±42.22 | 22.21±18.97 | 0.549 |
Liver HUs | 53.53±6.38 | 52.51±4.13 | 0.006 | 51.36±6.81 | 51.12±5.58 | 0.469 | 50.95±9.35 | 51.53±7.59 | 0.590 |
Spleen HUs | 45.50±3.20 | 43.63±3.49 | <0.001 | 45.4±3.67 | 44.95±3.56 | 0.397 | 44.83±3.51 | 42.13±3.59 | 0.011 |
Liver-to-spleen ratio | 1.180±0.144 | 1.213±0.149 | 0.300 | 1.142±0.178 | 1.142±0.134 | 0.841 | 1.140±0.165 | 1.233±0.217 | 0.043 |
Characteristics | Preoperative | 6 Months | 12 Months | 24 Months | p-value |
---|---|---|---|---|---|
BMI (kg/m2) | 25.88±3.61 | 23.93±5.04 | 22.78±1.67 | 22.74±2.37 | 0.02 |
Total cholesterol (mg/dL) | 187.05±29.57 | 155.79±31.15 | 160.54±38.34 | 159.84±36.67 | 0.03 |
HDL (mg/dL) | 42.51±7.77 | 41.82±9.64 | 46.68±11.15 | 45.39±10.96 | 0.03 |
LDL (mg/dL) | 112.45±42.80 | 90.71±22.71 | 92.27±33.89 | 88.81±27.87 | 0.33 |
Triglycerides (mg/dL) | 175.87±74.63 | 160.14±72.10 | 128.27±75.40 | 148.83±97.67 | 0.54 |
GOT (IU/L) | 24.68±8.14 | 25.77±8.82 | 32.70±38.24 | 28.04±6.79 | 0.20 |
GPT (IU/L) | 28.81±10.57 | 24.10±18.77 | 34.27±41.50 | 24.50±9.17 | 0.04 |
ALP (IU/L) | 68.39±24.35 | 80.57±23.44 | 80.70±23.85 | 77.77±22.97 | 0.11 |
γ-GTP (U/L) | 36.22±27.76 | 21.05±12.36 | 25.62±20.82 | 23.72±22.24 | 0.01 |
Liver HUs | 40.03±7.29 | 49.03±7.50 | 48.76±4.08 | 49.26±4.08 | <0.01 |
Spleen HUs | 46.39±2.98 | 44.47±3.47 | 44.33±4.02 | 44.89±3.76 | 0.03 |
Liver-to-spleen ratio | 0.836±0.141 | 1.115±0.234 | 1.109±0.155 | 1.102±0.134 | <0.01 |
Values are presented as number (%) or mean±standard deviation.. BMI, body mass index; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; GOT, glutamic oxaloacetic transaminase; GPT, glutamic pyruvic transaminase; ALP, alkaline phosphatase; γ-GTP, gamma glutamyl transpeptidase; HUs, Hounsfield units.
Values are presented as mean±standard deviation. BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; GOT, glutamic oxaloacetic transaminase; GPT, glutamic pyruvic transaminase; ALP, alkaline phosphatase; γ-GTP, gamma glutamyl transpeptidase; HUs, Hounsfield units.
Values are presented as mean±standard deviation. BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; GOT, glutamic oxaloacetic transaminase; GPT, glutamic pyruvic transaminase; ALP, alkaline phosphatase; γ-GTP, gamma glutamyl transpeptidase; HUs, Hounsfield units.