Kosin Medical Journal

Original articles

Intracranial aneurysms in autosomal dominant polycystic kidney disease: Jung Hyun Park; Kosin Med J. 2024;39(4):281-289. Published online December 6, 2024; DOI: https://doi.org/10.7180/kmj.24.138

1,223 View
17 Download

Abstract PDF PubReader ePub: Background
The incidence of intracranial aneurysms (ICA) is high in patients with autosomal dominant polycystic kidney disease (ADPKD). However, little is known regarding the optimal screening and treatment methods for ICA.
Methods
This study investigated the characteristics of ADPKD patients with ICA, analyzing each variable according to whether the ICA ruptured, and examined the outcomes according to the treatment method. Specifically, a retrospective study was conducted on the treatment of ICA patients with ADPKD at a single institution for 10 years, from 2013 to 2022.
Results
The mean age of the 17 enrolled ADPKD patients with ICA was 57.4 years. Surgical and endovascular treatment methods were used in four and 13 patients. Eleven patients had unruptured ICAs, and the remaining six patients had suffered subarachnoid hemorrhage (SAH). Two patients experienced neurological deficits after discharge. All patients with unruptured ICAs were discharged without any complications, although one of them underwent additional treatment 5 years later. Four patients with SAH had known ADPKD at the time of diagnosis (67%). As for the treatment method, 13 patients were treated with coiling. In a comparison of variables between unruptured ICA and SAH patients, the location of the ICA showed a statistically significant difference (p<0.05).
Conclusions
In ADPKD patients, diagnostic screening for the detection of ICA is essential, and with appropriate management, interventional endovascular treatment may be a good treatment option.

Diagnostic significance of transcranial Doppler ultrasonography in patients with subarachnoid hemorrhage and cerebral vasospasm: Jung Hyun Park; Kosin Med J. 2024;39(4):265-271. Published online December 2, 2024; DOI: https://doi.org/10.7180/kmj.24.139

1,085 View
27 Download

Abstract PDF PubReader ePub: Background
This study investigated the accuracy and usefulness of transcranial Doppler (TCD) ultrasonography as a diagnostic method in patients with subarachnoid hemorrhage (SAH) and cerebral vasospasm.
Methods
This retrospective study collected data from January 2022 to December 2023 at our institution, targeting patients with SAH caused by rupture of a cerebral aneurysm. TCD and brain computed tomographic angiography (CTA) were performed to diagnose cerebral vasospasm. The vessel diameters on CTA at the time of SAH occurrence and CTA 1 to 2 weeks after the occurrence were compared, and TCD was performed on a daily basis from 3 to 14 days after the occurrence of ictus.
Results
Among 152 patients with non-traumatic SAH over a 2-year period, 143 patients with SAH caused by ruptured cerebral aneurysms were enrolled. The mean age was 59.28±13.27 years. The modified Fisher grade was a statistically significant predictor of cerebral vasospasm (p<0.05). In addition, the Hunt-Hess grade also showed statistical significance (p<0.05). TCD showed high accuracy in predicting vasospasm. The sensitivity was 0.93 (95% confidence interval [CI], 0.87–0.97), specificity was 0.89 (95% CI, 0.81–0.96), positive predictive value was 0.92 (95% CI, 0.85–0.96), and negative predictive value was 0.92 (95% CI, 0.84–0.95).
Conclusions
TCD showed high accuracy in predicting the diagnosis of cerebral vasospasm. TCD is considered an essential diagnostic tool in the neurological management of cerebral vasospasm, which is a potentially fatal complication in SAH patients.

Predicting Factors Associated with Shunt Dependent Hydrocephalus after Aneurysmal Subarachnoid Hemorrhage: Yong Sook Park, Keum Whang, Yong Pyo Han; Kosin Med J. 2007;22(1):104-113. Published online June 30, 2007

495 View
0 Download

PDF

Usefulness of Acetazolamide-Enhanced Cerebral Perfusion SPECT in Subarachnoid Hemorrhage Patients: Seok Mo Lee, Sang Kyun Bae, Ha Yong Yum, Jae Gon Moon; Kosin Med J. 2000;15(1):65-70.

517 View
4 Download

PDF

First
Prev
Page of 1
Next
Last

Search