Kosin Medical Journal

Case reports

Primary gastric leiomyosarcoma: a case report and literature review: Yedaun Lee; Kosin Med J. 2024;39(1):60-65. Published online August 18, 2023; DOI: https://doi.org/10.7180/kmj.23.118

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After separating gastrointestinal (GI) stromal tumors from true smooth muscle tumors of the GI tract, leiomyosarcoma (LMS) of the GI tract has become a rare tumor. Gastric LMS is extremely rare and accounts for 0.1% of all cases of LMS in the GI tract. There are few English-language reports of gastric LMS describing radiologic findings. Here, we report a case of gastric LMS and review the recent literature focusing on radiologic findings. An 80-year-old female patient was referred for evaluation of a gastric mass accompanied by severe anemia. The physical examination revealed no specific findings except for an anemic conjunctiva. Laboratory data showed a low hemoglobin level of 5.1 g/dL. Endoscopy revealed a huge subepithelial mass in the posterior wall of the gastric body. Contrast-enhanced computed tomographic images showed an intraluminal protruding enhancing mass with an internal stalk appearance in the gastric body. There was no internal necrosis or calcification. The patient underwent subtotal gastrectomy and was diagnosed with primary gastric LMS. The diagnosis of gastric LMS is challenging due to its rarity. Our case report suggests that the presence of an internal stalk or spouting appearance can help prompt the radiologist to consider gastric LMS in the differential diagnosis.

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Pleomorphic gastric leiomyosarcoma with retroperitoneal extension and hepatic metastasis: A case report
Kun Huang, Wen Wang, Mei-Ling Xu, Yun-Shen He, Jiang-Ying Zhao, Xiao-Feng Hu
World Journal of Gastrointestinal Surgery.2026;[Epub] CrossRef

Squamous cell carcinoma of the pancreas with a pancreatic intraductal papillary mucinous neoplasm: a case report: Nam Kyung Lee; Kosin Med J. 2024;39(1):71-74. Published online August 17, 2023; DOI: https://doi.org/10.7180/kmj.23.123

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Squamous cell carcinoma (SCC) of the pancreas is very rare. No reports have described SCC accompanied by intraductal papillary mucinous neoplasm (IPMN) of the pancreas. This report presents the first known case of SCC with IPMN of the pancreas in a 71-year-old man, with a focus on radiologic findings. Here, the imaging features of SCC with IPMN of the pancreas were similar to those of IPMN of the pancreas with high-risk stigmata features.

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NRG1 fusion-positive solid tumors: clinical detection, genomic landscape, and real-world data in pancreatic cancer
Alison M Schram, Soo-Ryum Yang, Genessa Kahn, Rogelio Velasco, Matteo Repetto, Richard Kinh Gian Do, Sara DiNapoli, Purvil Sukhadia, Megan Troxel, Kerem Ozcan, Zeynep Tarcan, Marc Ladanyi, James J Harding, Alexander Drilon, Olca Basturk, Eileen M O’Reilly
JNCI: Journal of the National Cancer Institute.2025;[Epub] CrossRef
Invasive squamous cell carcinoma arising from an intraductal oncocytic papillary neoplasm demonstrating shared ATP1B1::PRKACA gene fusion
Wai Szeto, Safa Alshaikh, Javier A. Arias-Stella, Yuman Fong, Rifat Mannan
Human Pathology Reports.2024; 37: 300745. CrossRef

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