KOSIN UNIVERSITY COLLEGE OF MEDICINE
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- Clinical readiness of artificial intelligence for treat-to-target management in inflammatory bowel disease: from scores to decisions
- You Jin Choi, Seom Gim Kong, So Yoon Choi
- Kosin Med J. 2026;41(3):185-202. Published online September 30, 2026
- DOI: https://doi.org/10.7180/kmj.26.197
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- Artificial intelligence (AI) is increasingly used in inflammatory bowel disease (IBD), particularly for endoscopy, histology, transmural imaging, and prediction of treatment response. However, strong diagnostic or predictive performance does not necessarily confer clinical utility. This narrative review traces the development of AI in IBD from objective disease assessment and outcome prediction to therapeutic decision support within a treat-to-target framework. Endoscopic AI has the most mature evidence base, while applications in histology and transmural imaging are at earlier stages of clinical translation. Models of treatment response can stratify patients by the likelihood of response, remission, relapse, or treatment sustainability; most, however, remain prognostic rather than prescriptive. We therefore propose the clinical readiness of AI in IBD framework, comprising analytical validity, clinical validity, generalizability, workflow utility, decision utility, and clinical impact. The strongest evidence concerns disease measurement and prediction; evidence that AI-informed or AI-guided strategies improve treatment decisions and patient outcomes remains limited. Future research should prioritize external validation, prospective evaluation in clinical workflows, comparative trials of prespecified AI-informed or AI-guided treatment strategies, and patient-important outcomes.
- Long-term outcomes and multidisciplinary management in children with anorectal malformations
- Hira Ahmad, Ashish Chogle, Zoe Flyer, Donald Shaul, Gyu Min Yeon, Seom Gim Kong, So Yoon Choi
- Kosin Med J. 2025;40(3):167-176. Published online September 23, 2025
- DOI: https://doi.org/10.7180/kmj.25.120
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- Anorectal malformations (ARMs) represent a spectrum of congenital anomalies affecting the distal rectum and anus, often accompanied by genitourinary and spinal defects. Despite advances in surgical techniques, long-term gastrointestinal dysfunction, such as fecal incontinence and chronic constipation, remains prevalent in individuals with various types of ARMs. These persistent challenges contribute to considerable psychosocial morbidity, including anxiety, depression, and diminished quality of life. Integrated mental health, nutritional, and social support are essential to address the complex needs of ARM patients. Effective management requires a stepwise approach, beginning with dietary modifications and behavioral therapy, and progressing to pharmacological, surgical, and neuromodulatory interventions as clinically indicated. Long-term follow-up and structured transitional care, especially during adolescence, are critical for promoting medical autonomy and addressing sexual and reproductive health. International and national registries support data standardization and multicenter collaboration. Future research should prioritize identifying predictive biomarkers, refining neuromodulation, characterizing microbiome-related mechanisms, and utilizing artificial intelligence to personalize care. Sustained multidisciplinary efforts are critical to improving functional outcomes and overall quality of life in children with ARMs.
- Clinical Features and Factors Associated with the Frequency of Phototherapy in Premature Birth Gestation < 35 Weeks and Birth Weight ≤2,500 g
- So Yoon Choi, Ho Yeon Hwang, Yoo Rha Hong, Yu Jin Jung
- Kosin Med J. 2012;27(2):133-139. Published online December 27, 2012
- DOI: https://doi.org/10.7180/kmj.2012.27.2.133
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Objectives Clinical features according to the frequency of phototherapy and clinical risk factors on the number of phototherapy were investigated in premature births with gestation <35 weeks and birth weight ≤2,500 g.
Methods The 186 infants with gestation <35 weeks and birth weight ≤2,500 g were admitted to the neonatal intensive care unit of Kosin University Gospel Hospital from March 2009 to August 2010. The 171 infants were alive and had jaundice requiring phototherapy. Phototherapy was usually started to 50-70% of the maximal bilirubin level. They were divided into two groups according to the frequency of phototherapy as single phototherapy group (group I) and multiple phototherapy group (group II). We retrospectively reviewed the medical records of all patients.
Results The mean gestational age and birth weight of group I were 31.0±2.9 weeks and 1,596±485 g and those of group II were 31.1±2.6 weeks and 1,592±430 g. Compared with group I, albumin and Apgar score at 1 minute of group II were significantly higher and the day of peak bilirubin was also late. Duration of phototherapy in group II was statistically longer than that group I but duration of ventilator and aminophylline use for apnea was significantly shorter. The frequency of antibiotic use, incidence of bronchopulmonary dysplasia (BPD), and intraventricular hemorrhage (IVH) of group II were significantly lower than those of group I.
Conclusions The day of peak bilirubin was late and the frequency of antibiotic use, incidence of BPD, and IVH were low in group II. The aggressive phototherapy may be considered in premature births with jaundice.
- The Incidence and Pathologic Analysis for Patients with Large Gastric Tumors over 8cm
- So Yoon Choi, Young Jin Lee, Ji Hyun Ahn, Min Jung Jung, Hee Kyung Chang
- Kosin Med J. 2007;22(1):43-48. Published online June 30, 2007
- 1,047 View
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