- Current understanding of modulated electro-hyperthermia in cancer treatment
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Sungmin Kim, Jesang Yu, Jihun Kang, Yunkyung Kim, Taek Yong Ko
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Kosin Med J. 2024;39(3):160-168. Published online September 23, 2024
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DOI: https://doi.org/10.7180/kmj.24.127
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 Abstract
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- Traditional hyperthermia involves increasing the temperature at the tumor site to above 39 ℃, inducing death in cancer cells. Although hyperthermia is an effective cancer treatment, its clinical application has decreased due to potential complications, including damage to surrounding normal tissue. In recent years, modulated electro-hyperthermia (mEHT) has emerged as an effective and safe treatment modality. mEHT selectively heats tumor cells to 42–43 °C, while reducing the average temperature in the treatment area, including the surrounding normal tissue, compared to conventional methods. Additionally, mEHT may be used in combination with systemic chemotherapy and radiation therapy in tumor treatment, providing a synergistic effect to increase efficacy. As chemotherapy and radiation therapy technologies advance, the application of combined mEHT may improve clinical outcomes. In this study, we review and discuss reports on the clinical outcomes of mEHT combined with chemotherapy and/or radiation therapy, which are established anticancer treatments.
- Sonozaki syndrome (pustulotic arthro-osteitis) causing anterior chest pain: a case report
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Taek Yong Ko
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Received July 3, 2024 Accepted August 15, 2024 Published online November 7, 2024
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DOI: https://doi.org/10.7180/kmj.24.128
[Epub ahead of print]
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Abstract
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- Sonozaki syndrome is an exceptionally rare chronic rheumatic disorder characterized by pustulosis on the palms and soles, as well as arthritis and osteitis. This syndrome belongs to the category of spondyloarthritis, which includes psoriatic arthritis. Pustules are concentrated on the palms and soles, whereas arthro-osteitis predominantly affects the sternoclavicular and costochondral joints. This report presents the case of a 32-year-old man with a 2-month history of worsening anterior chest wall pain and pustular eruptions on the palms and soles.
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KOSIN UNIVERSITY COLLEGE OF MEDICINE
