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Jin Young Lee 3 Articles
The clinical features and infectious etiologies of acute diarrhea in immunocompromised hosts
Jin Young Lee, Ye Na Kim, Namho Kim, Kyoung Soon Cho, Ji Young Park
Kosin Med J. 2017;32(2):191-203.   Published online December 29, 2017
DOI: https://doi.org/10.7180/kmj.2017.32.2.191
  • 2,227 View
  • 49 Download
  • 3 Citations
Abstract PDFPubReader   ePub   
Objectives

The acute diarrhea is a common complaint among immunocompromised hosts, and may cause life threatening event. The infectious etiologies vary depending on virus, bacteria, and parasites. The most common etiology of acute gastroenteritis is known as enteric virus in Korea.1 But there are few studies about the infectious etiology of acute gastroenteritis in immunocompromised hosts.23 The aim of this study was to investigate the infectious etiologies of acute diarrhea in immunocompromised hosts.

Methods

Seventy three patients were enrolled prospectively in a university hospital from January 2013 to July 2014. Immunocompromised hosts included above 65-year-old people, patients with chronic diseases, solid organ or stem cell transplants, solid organ malignancies, hematologic malignancies, immunosuppressive or steroid taking patients. The clinical data were collected and stool samples collected during diarrhea were undergone laboratory analysis for enteric viruses and bacterial enteropathogens including Salmonella spp., Shigella spp., and Clostridium difficile.

Results

Fifty five patients were analyzed as follows : above 65 year-old people were 36 cases (66%), previous antibiotic usage was 22 cases (41.5%). 44 cases (81.1%) were admitted to general ward whereas 9 cases to ICU (17%). 41 cases (73.6%) were treated with antibiotics. Positive C. difficile toxin assays were 6 cases (11.9%). Other infectious etiologies were not found.

Conclusions

C. difficile infection was more common infectious etiology while enteric viruses and other bacteria are not associated with acute diarrhea among immunocompromised hosts in this study. So C. difficile infection must be considered preferentially in immunocompromised hosts with acute diarrhea.

Citations

Citations to this article as recorded by  
  • Evaluation of the detection of diarrhoea-associated RNA viruses in immunocompromised children in Iran
    Shokouh Yasaie, Seyed Dawood Mousavi Nasab, Saeed Shams, Atousa Ferdousi, Hooman Kaghazian
    Infection Prevention in Practice.2024; 6(3): 100370.     CrossRef
  • Prevalence of Human Adenovirus, Epstein-Barr Virus, and Cytomegalovirus in Pediatric Hematologic Diseases in Iran
    Shokouh Yasaie, Atousa Ferdousi, Seyed Dawood Mousavi Nasab, Hooman Kaghazian, Saeed Shams
    Infection Epidemiology and Microbiology.2024; 10(1): 51.     CrossRef
  • Mucoprotectants
    Sung Eun Kim
    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2022; 22(2): 108.     CrossRef
Therapeutic comparison of Surgery combined with chemotherapy and chemotherapy alone for Primary Gastrointestinal Lymphoma: A single center study
Je Hun Kim, Ho Sup Lee, Jun Seop Lee, Jin Young Lee, Su Young Kim, Cheol Su Kim, Joung Wook Yang, Ga In You
Kosin Med J. 2015;30(1):29-39.   Published online January 20, 2015
DOI: https://doi.org/10.7180/kmj.2015.30.1.29
  • 1,364 View
  • 3 Download
Abstract PDFPubReader   ePub   
Abstract Objectives

There is still no consensus on the optimal treatment for primary gastrointestinal lymphoma (PGIL). The aim of this study was to compare surgery combined with chemotherapy and chemotherapy alone in PGIL.

Methods

We retrospectively reviewed and analyzed the treatment outcomes of 107 patients with primary gastrointestinal lymphoma diagnosed between March 1999 and December 2009 at Kosin University Gospel Hospital. Patients were divided into two groups: 35 patients who underwent surgery combined with chemotherapy (group A) and 72 patients who were treated with chemotherapy alone (group B). And we analyzed prognostic factors associated with short survival.

Results

The 5-year progression free survival rates (PFS) of group A and B were 86.7% and 66.1%, respectively (P = 0.037), while the 5-year overall survival rates (OS) were 86.8% and 68.4%, respectively (P = 0.129). In multivariate analysis, Both PFS and OS were not changed by treatment strategies (surgery combined with chemotherapy or chemotherapy only). The international prognostic index (IPI) was the only independent predictive factor for PFS.

Conclusions

In our study, surgery combined with chemotherapy and chemotherapy only make no difference of survival rate. And further randomized prospective studies are needed to confirm a treatment strategies at improving survival outcomes in PGIL patients.

Comparison of Social Nicotine Dependence Using the KTSND-K Questionnaire between patients with lung cancer and non-cancer people
Jin Young Lee, Chul Ho Oak, Tae Won Jang, Maan Hong Jung, Seong Jin Nam, Su Kyung Son, Ji Hyun Lee, Eun Joo Jo, Sang Joon Lee
Kosin Med J. 2015;30(1):51-58.   Published online January 20, 2015
DOI: https://doi.org/10.7180/kmj.2015.30.1.51
  • 1,420 View
  • 8 Download
  • 1 Citations
Abstract PDFPubReader   ePub   
Abstract Objectives

Smoking is one of the most important leading causes of lung cancer. Smoking habit is recognized as nicotine dependence, which consists of physical and psychosocial dependence. To evaluate social nicotine dependence, the Kano Test for Social Nicotine Dependence (KTSND) working group developed a new questionnaire. We examined the social nicotine dependence among high school students, university students and patients with lung cancer.

Method

We applied Korean version of KTSND(KTSND-K) questionnaire to high school students, university students and patients with lung cancer. Complete data obtained from the 1333 responders were analyzed.

Results

Among the responders, current smokers, past-smokers, and never-smokers were 17.3%, 16.4%, and 66.3% respectively. According to smoking status, the total KTSND-K scores of current smokers were significantly higher than those of past-smokers, and of never-smokers (17.7±6.6 versus 13.7±5.7, and 10.9±5.15, P<0.001). The total KTSND-K scores of males were higher than those of females, suggesting that males have a propensity for depending nicotine socially much more than females (13.2±6.2 and 11.7±5.7 respectively, P<0.05). And the total KTSND scores of the patients with lung cancer, medical students, nursing students, and high school students were 11.2±3.8, 14.9±4.8, 14.6±5.8 and 15.6±5.9 respectively. The scores of patients with lung cancer were significantly lower than non-cancer people(P<0.01). Our study suggested that the KTSND-K questionnaire could be a useful method to evaluate psychosocial aspects of smoking in patients with lung cancer and non-cancer people.

Citations

Citations to this article as recorded by  
  • Assessment of physiological and psychological dependence of tobacco use among patients visiting the tobacco cessation center in the tertiary institute of Shimla–Himachal Pradesh
    Deepak Gurung, Vinay Kumar Bhardwaj, Shailee Fotedar
    Santosh University Journal of Health Sciences.2023; 9(2): 175.     CrossRef

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